SEARCH FOR A PLATELET-ACTIVATING FACTOR RECEPTOR IN THE TRYPANOSOMA CRUZI PROTEOME: A POTENTIAL TARGET FOR CHAGAS DISEASE CHEMOTHERAPY

Search for a platelet-activating factor receptor in the Trypanosoma cruzi proteome: a potential target for Chagas disease chemotherapy

Chagas disease (CD) causes the highest burden of parasitic diseases in the Western Hemisphere and is therefore a priority for drug research and development.Platelet-activating factor (PAF) causes the CD parasite Trypanosoma cruzi to differentiate, which SLEEP RELAX EXTRACT suggests that the parasite may express PAF receptors.Here, we explored the T

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Repeated oxytocin prevents central sensitization by regulating synaptic plasticity via oxytocin receptor in a chronic migraine mouse model

Abstract Background Central sensitization is one of the characters of chronic migraine (CM).Aberrant synaptic plasticity can induce central sensitization.Oxytocin (OT), which is a hypothalamic hormone, plays an important Bowls antinociceptive role.However, the antinociceptive effect of OT and the underlying mechanism in CM remains unclear.Therefore

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Identification key to Central European species of Trachytes (Acari: Uropodina) with redescriptions, ecology and distribution of Slovak species

A total of 23 uropodine species of the genus Trachytes (Acari, Mesostigmata) are reliably recorded to occur in Central Europe Seed and included in identification keys for adults (23 spp.) and deutonymphal stages (9 spp.), respectively.For the first time, the diagnostic characters of deutonymphs of the species T.baloghi, T.minima, T.minimasimilis, T

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